MolNFT v1 · #34931 · protein
Phosphorylated crk-II
2DVJ · V-crk sarcoma virus CT10 oncogene homolog, isoform a: “Phosphorylated crk-II”. Solution nmr, 2 pockets (best druggability 0.36). MolNFT v1 #34931 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2DVJ
- Type
- protein
- Length
- 228 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- V-crk sarcoma virus CT10 oncogene homolog, isoform a
- UniProt
- Q96HJ0
- Pockets
- 2 · best druggability 0.36
Structure
solution nmr · 1 distinct chain · 6% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-crk sarcoma virus CT10 oncogene homolog, isoform a | protein | 228 | 6% helix, 12% strand | Q96HJ0 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 112 | 0.36 | 0.73 | 23 | empty |
| 2 | 51 | 0.30 | 0.75 | 13 | empty |
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 2DVJ · phosphorylated Crk-II · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96HJ0
- Elsewhere: RCSB PDB 2DVJ · PDBe 2DVJ · UniProt Q96HJ0
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