MolNFT v1 · #34851 · protein
Three dimensional structure of a goat signalling protein secreted during involution
2DSZ · Chitinase-3-like protein 1: “Three dimensional structure of a goat signalling protein secreted during involution”. X-ray diffraction, 2 ligands (MAN, NAG), 3 pockets (best druggability 0.57). MolNFT v1 #34851 on GenesisL1: 3D…
- PDB
- 2DSZ
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chitinase-3-like protein 1
- UniProt
- Q8SPQ0
- Ligands
- MAN, NAG
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chitinase-3-like protein 1 | protein | 361 | 36% helix, 24% strand | Q8SPQ0 |
Ligands and binding sites
- MAN · alpha-D-mannopyranose · sugar · 3 copies
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 249 | 0.57 | 0.78 | 33 | empty |
| 2 | 285 | 0.56 | 0.77 | 37 | empty |
| 3 | 53 | 0.29 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 2DSZ · Three dimensional structure of a goat signalling protein secreted during involution · the same entry in another collection · chain A against A, TM-score 1.00
- Q8SPQ0 · AlphaFold monomer V2.0 prediction for chitinase-3-like protein 1 (Q8SPQ0) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8SPQ0
- Elsewhere: RCSB PDB 2DSZ · PDBe 2DSZ · UniProt Q8SPQ0
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