MolNFT v1 · #34696 · protein

Solution structure of rsgi ruh-063, an N-terminal domain of syntaxin 12 from human cdna

2DNX · Syntaxin-12: “Solution structure of rsgi ruh-063, an N-terminal domain of syntaxin 12 from human cdna”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1 #34696 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2DNX
Type: protein
Length: 130 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Syntaxin-12
UniProt: Q86Y82
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Syntaxin-12	protein	130	76% helix, 0% strand	Q86Y82

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	104	0.41	0.76	14	empty

Compared structures

2DNX · Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA · the same entry in another collection · chain A against A, TM-score 1.00
Q86Y82 · AlphaFold monomer V2.0 prediction for syntaxin-12 (Q86Y82) · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86Y82
Elsewhere: RCSB PDB 2DNX · PDBe 2DNX · UniProt Q86Y82

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