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MolNFT v1 · #34614 · protein

Solution structure of the irf domain of human interferon regulator factors 4

2DLL · Interferon regulatory factor 4: “Solution structure of the irf domain of human interferon regulator factors 4”. Solution nmr, 1 pocket (best druggability 0.58). MolNFT v1 #34614 on GenesisL1: 3D structure, binding sites and pockets…

PDB
2DLL
Type
protein
Length
121 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Interferon regulatory factor 4
UniProt
Q15306
Pockets
1 · best druggability 0.58

Structure

solution nmr · 1 distinct chain · 32% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AInterferon regulatory factor 4protein12132% helix, 16% strandQ15306

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12180.580.8026empty

Compared structures

  • 2DLL · Solution structure of the IRF domain of human interferon regulator factors 4 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q15306 · AlphaFold monomer V2.0 prediction for interferon regulatory factor 4 (Q15306) · a predicted model of the same protein · chain A against A, TM-score 0.82

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