MolNFT v1 · #34567 · protein
Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the apo-form
2DKA · Phosphoacetylglucosamine mutase: “Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase…”. X-ray diffraction, 12 pockets (best druggability 0.73). MolNFT v1 #34567 on GenesisL1: 3D…
- PDB
- 2DKA
- Type
- protein
- Length
- 980 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoacetylglucosamine mutase
- EC
- 5.4.2.3
- UniProt
- Q9P4V2
- Pockets
- 12 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoacetylglucosamine mutase (EC 5.4.2.3) | protein | 519 | 42% helix, 19% strand | Q9P4V2 |
| B | Phosphoacetylglucosamine mutase (EC 5.4.2.3) | protein | 461 | 42% helix, 18% strand | Q9P4V2 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 520 | 0.73 | 0.82 | 74 | empty |
| 2 | 309 | 0.71 | 0.84 | 43 | empty |
| 3 | 174 | 0.51 | 0.78 | 28 | empty |
| 4 | 199 | 0.50 | 0.76 | 31 | empty |
| 5 | 115 | 0.48 | 0.80 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 878 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 2DKA · Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9P4V2 · AlphaFold monomer V2.0 prediction for phosphoacetylglucosamine mutase (Q9P4V2) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9P4V2
- Elsewhere: RCSB PDB 2DKA · PDBe 2DKA · UniProt Q9P4V2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.