MolNFT v1 · #34514 · protein

Solution structure of the zz domain of zinc finger swim domain containing protein 2

2DIP · Zinc finger swim domain-containing protein 2: “Solution structure of the zz domain of zinc finger swim domain containing protein 2”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.30). MolNFT v1 #34514 on GenesisL1: 3D…

PDB: 2DIP
Type: protein
Length: 98 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Zinc finger swim domain-containing protein 2
UniProt: Q8NEG5
Ligands: ZN
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 8% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger swim domain-containing protein 2	protein	98	8% helix, 12% strand	Q8NEG5

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.30	0.75	17	empty

Compared structures

2DIP · Solution structure of the ZZ domain of Zinc finger SWIM domain containing protein 2 · the same entry in another collection · chain A against A, TM-score 1.00
Q8NEG5 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase ZSWIM2 (Q8NEG5) · a predicted model of the same protein · chain A against A, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NEG5
Elsewhere: RCSB PDB 2DIP · PDBe 2DIP · UniProt Q8NEG5

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