MolNFT v1 · #34469 · protein

Solution structure of the second RNA binding domain in nucleolysin tiar

2DH7: “Solution structure of the second RNA binding domain in nucleolysin tiar”. Solution nmr, 1 pocket (best druggability 0.36). MolNFT v1 #34469 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2DH7
Type: protein
Length: 105 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleolysin tiar
UniProt: Q01085
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 16% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleolysin tiar	protein	105	16% helix, 23% strand	Q01085

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.36	0.74	13	empty

Compared structures

2DH7 · Solution structure of the second RNA binding domain in Nucleolysin TIAR · the same entry in another collection · chain A against A, TM-score 1.00
Q01085 · AlphaFold monomer V2.0 prediction for nucleolysin tiar (Q01085) · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01085
Elsewhere: RCSB PDB 2DH7 · PDBe 2DH7 · UniProt Q01085

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