MolNFT v1 · #34261 · protein

Solution structure of second pwwp domain of WHSC1L1 protein

2DAQ · WHSC1L1 protein, isoform long: “Solution structure of second pwwp domain of WHSC1L1 protein”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #34261 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2DAQ
Type: protein
Length: 110 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: WHSC1L1 protein, isoform long
UniProt: Q9BZ95
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 19% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	WHSC1L1 protein, isoform long	protein	110	19% helix, 22% strand	Q9BZ95

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	208	0.48	0.75	28	empty

Compared structures

2DAQ · Solution structure of second PWWP domain of WHSC1L1 protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9BZ95 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase NSD3 (Q9BZ95) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BZ95
Elsewhere: RCSB PDB 2DAQ · PDBe 2DAQ · UniProt Q9BZ95

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