MolNFT v1 · #34209 · protein

Solution structure of rsgi ruh-048, a GTF2I domain in human cdna

2D99 · General transcription factor II-I repeat domain-containing…: “Solution structure of rsgi ruh-048, a GTF2I domain in human cdna”. Solution nmr, 1 pocket (best druggability 0.33). MolNFT v1 #34209 on GenesisL1: 3D structure, binding…

PDB: 2D99
Type: protein
Length: 90 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: General transcription factor II-I repeat domain-containing protein 1
UniProt: Q9UHL9
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 37% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	General transcription factor II-I repeat domain-containing protein 1	protein	90	37% helix, 9% strand	Q9UHL9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.33	0.77	13	empty

Compared structures

2D99 · Solution Structure of RSGI RUH-048, a GTF2I domain in human cDNA · the same entry in another collection · chain A against A, TM-score 1.00
Q9UHL9 · AlphaFold monomer V2.0 prediction for general transcription factor II-I repeat… · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UHL9
Elsewhere: RCSB PDB 2D99 · PDBe 2D99 · UniProt Q9UHL9

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