MolNFT v1 · #34096 · protein

Crystal structure of a 49K fragment of HAP1 (flgk)

2D4Y · Flagellar hook-associated protein 1: “Crystal structure of a 49K fragment of HAP1 (flgk)”. X-ray diffraction, 7 pockets (best druggability 0.67). MolNFT v1 #34096 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2D4Y
Type: protein
Length: 854 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flagellar hook-associated protein 1
UniProt: P0A1J5
Pockets: 7 · best druggability 0.67

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flagellar hook-associated protein 1	protein	429	51% helix, 18% strand	P0A1J5
B	Flagellar hook-associated protein 1	protein	425	49% helix, 18% strand	P0A1J5

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	586	0.67	0.77	55	empty
2	242	0.59	0.80	33	empty
3	308	0.58	0.77	39	empty
4	337	0.57	0.76	42	empty
5	99	0.42	0.78	18	empty

Interfaces

1 interface between chains.

A–B · 733 Å² buried · 17 hydrogen bonds · protein-protein

Compared structures

2D4Y · Crystal structure of a 49K fragment of HAP1 (FlgK) · the same entry in another collection · chain A against A, TM-score 1.00
P0A1J5 · AlphaFold monomer V2.0 prediction for flagellar hook-associated protein 1 (P0A1J5) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A1J5
Elsewhere: RCSB PDB 2D4Y · PDBe 2D4Y · UniProt P0A1J5

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