MolNFT v1 · #34062 · protein
Crystal structure of escherichia COLI sufc, an ATPase compenent of the suf iron-sulfur cluster assembly machinery
2D3W · Probable ATP-dependent transporter sufc: “Crystal structure of escherichia COLI sufc, an ATPase compenent of the suf iron-sulfur cluster assembly…”. X-ray diffraction, 13 pockets (best druggability 0.73). MolNFT v1 #34062 on…
- PDB
- 2D3W
- Type
- protein
- Length
- 972 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable ATP-dependent transporter sufc
- UniProt
- P77499
- Pockets
- 13 · best druggability 0.73
Structure
x-ray diffraction · 4 distinct chains · 37% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable ATP-dependent transporter sufc | protein | 244 | 36% helix, 26% strand | P77499 |
| B | Probable ATP-dependent transporter sufc | protein | 244 | 39% helix, 25% strand | P77499 |
| C | Probable ATP-dependent transporter sufc | protein | 241 | 38% helix, 27% strand | P77499 |
| D | Probable ATP-dependent transporter sufc | protein | 243 | 34% helix, 26% strand | P77499 |
Pockets
13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 140 | 0.73 | 0.92 | 28 | empty |
| 2 | 92 | 0.72 | 0.95 | 23 | empty |
| 3 | 447 | 0.65 | 0.78 | 51 | empty |
| 4 | 283 | 0.62 | 0.80 | 59 | empty |
| 5 | 61 | 0.52 | 0.86 | 18 | empty |
Interfaces
4 interfaces between chains.
- A–B · 849 Ų buried · 1 hydrogen bond · protein-protein
- C–D · 789 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 142 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 138 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2D3W · Crystal Structure of Escherichia coli SufC, an ATPase compenent of the SUF iron-sulfur… · the same entry in another collection · chain D against D, TM-score 1.00
- P77499 · AlphaFold monomer V2.0 prediction for probable ATP-dependent transporter sufc (P77499) · a predicted model of the same protein · chain C against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P77499
- Elsewhere: RCSB PDB 2D3W · PDBe 2D3W · UniProt P77499
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