MolNFT v1 · #33931 · protein

Crystal structure of tbp-interacting protein (tk-TIP26) and implications for its inhibition mechanism of the interaction between tbp and tata-DNA

2CZR: “Crystal structure of tbp-interacting protein (tk-TIP26) and implications for its inhibition mechanism of the…”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.32). MolNFT v1 #33931 on GenesisL1: 3D structure…

PDB: 2CZR
Type: protein
Length: 226 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tbp-interacting protein
Ligands: ZN
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tbp-interacting protein	protein	226	32% helix, 36% strand	—

Ligands and binding sites

ZN · Zinc ion · metal · chains A
GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.32	0.74	16	empty

Compared structures

2CZR · Crystal structure of TBP-interacting protein (Tk-TIP26) and implications for its… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2CZR · PDBe 2CZR

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