MolNFT v1 · #33890 · protein

Crystal structure of thioesterase superfamily MEMBER2 from mus musculus

2CY9 · Thioesterase superfamily member 2: “Crystal structure of thioesterase superfamily MEMBER2 from mus musculus”. X-ray diffraction, 1 pocket (best druggability 0.43). MolNFT v1 #33890 on GenesisL1: 3D structure, binding sites and…

PDB: 2CY9
Type: protein
Length: 255 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thioesterase superfamily member 2
EC: 3.1.2.-
UniProt: Q9CQR4
Pockets: 1 · best druggability 0.43

Structure

x-ray diffraction · 2 distinct chains · 18% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thioesterase superfamily member 2 (EC 3.1.2.-)	protein	122	10% helix, 40% strand	Q9CQR4
B	Thioesterase superfamily member 2 (EC 3.1.2.-)	protein	133	25% helix, 36% strand	Q9CQR4

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.43	0.80	16	empty

Interfaces

1 interface between chains.

A–B · 632 Å² buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 15 modified (engineered).

Compared structures

2CY9 · Crystal structure of thioesterase superfamily member2 from Mus musculus · the same entry in another collection · chain A against A, TM-score 1.00
Q9CQR4 · AlphaFold monomer V2.0 prediction for acyl-coenzyme a thioesterase 13 (Q9CQR4) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9CQR4
Elsewhere: RCSB PDB 2CY9 · PDBe 2CY9 · UniProt Q9CQR4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.