MolNFT v1 · #33854 · protein

Crystal structure of ribonuclease inhibitor barstar

2CX6 · Hypothetical protein yhco: “Crystal structure of ribonuclease inhibitor barstar”. X-ray diffraction, 1 pocket (best druggability 0.27). MolNFT v1 #33854 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2CX6
Type: protein
Length: 180 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein yhco
UniProt: P64618
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Hypothetical protein yhco	protein	90	43% helix, 19% strand	P64618

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.27	0.74	11	empty

Interfaces

1 interface between chains.

A–B · 522 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

2CX6 · Crystal structure of ribonuclease inhibitor Barstar · the same entry in another collection · chain A against A, TM-score 1.00
P64618 · AlphaFold monomer V2.0 prediction for uncharacterized protein yhco (P64618) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P64618
Elsewhere: RCSB PDB 2CX6 · PDBe 2CX6 · UniProt P64618

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