MolNFT v1 · #33076 · protein

Structural basis of the nucleotide driven conformational changes in the aaa domain of transcription activator pspf

2C98 · Psp operon transcriptional activator: “Structural basis of the nucleotide driven conformational changes in the aaa domain of transcription activator…”. X-ray diffraction, 1 ligand (ADP), 3 pockets (best druggability 0.41). MolNFT v1…

PDB: 2C98
Type: protein
Length: 244 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Psp operon transcriptional activator
UniProt: P37344
Ligands: ADP
Pockets: 3 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Psp operon transcriptional activator	protein	244	46% helix, 14% strand	P37344

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	112	0.41	0.76	20	ADP
2	99	0.41	0.77	16	empty
3	89	0.40	0.78	14	empty

Compared structures

2C98 · Structural basis of the nucleotide driven conformational changes in the AAA domain of… · the same entry in another collection · chain A against A, TM-score 1.00
P37344 · AlphaFold monomer V2.0 prediction for psp operon transcriptional activator (P37344) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P37344
Elsewhere: RCSB PDB 2C98 · PDBe 2C98 · UniProt P37344

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