MolNFT v1 · #32978 · protein
Aurora a kinase activated mutant (T287D) in complex with a 5-aminopyrimidinyl quinazoline inhibitor
2C6E: “Aurora a kinase activated mutant (T287D) in complex with a 5-aminopyrimidinyl quinazoline inhibitor”. X-ray diffraction. MolNFT v1 #32978 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2C6E
- Type
- protein
- Length
- 497 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O14965
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 251 | — | O14965 |
| B | — | protein | 246 | — | O14965 |
Compared structures
- 2C6E · Aurora A kinase activated mutant (T287D) in complex with a 5- aminopyrimidinyl… · the same entry in another collection · chain A against A, TM-score 1.00
- O14965 · AlphaFold monomer V2.0 prediction for aurora kinase a (O14965) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14965
- Elsewhere: RCSB PDB 2C6E · PDBe 2C6E · UniProt O14965
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