MolNFT v1 · #32965 · protein
Crystal structure of the non-catalytic B subunit of a-type ATPase from M. mazei GO1
2C61 · A-type ATP synthase non-catalytic subunit B: “Crystal structure of the non-catalytic B subunit of a-type ATPase from M. mazei GO1”. X-ray diffraction, 10 pockets (best druggability 0.87). MolNFT v1 #32965 on GenesisL1: 3D structure…
- PDB
- 2C61
- Type
- protein
- Length
- 856 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- A-type ATP synthase non-catalytic subunit B
- EC
- 3.6.3.14
- UniProt
- Q60187
- Pockets
- 10 · best druggability 0.87
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | A-type ATP synthase non-catalytic subunit B (EC 3.6.3.14) | protein | 431 | 37% helix, 22% strand | Q60187 |
| B | A-type ATP synthase non-catalytic subunit B (EC 3.6.3.14) | protein | 425 | 37% helix, 24% strand | Q60187 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 345 | 0.87 | 0.96 | 42 | empty |
| 2 | 1191 | 0.78 | 0.80 | 100 | empty |
| 3 | 128 | 0.42 | 0.76 | 22 | empty |
| 4 | 95 | 0.41 | 0.77 | 21 | empty |
| 5 | 116 | 0.40 | 0.75 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 2419 Ų buried · 39 hydrogen bonds · protein-protein
Compared structures
- 2C61 · Crystal structure of the non-catalytic B subunit of A-type ATPase from M. mazei Go1 · the same entry in another collection · chain A against A, TM-score 1.00
- Q60187 · AlphaFold monomer V2.0 prediction for V-type ATP synthase beta chain (Q60187) · a predicted model of the same protein · chain B against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60187
- Elsewhere: RCSB PDB 2C61 · PDBe 2C61 · UniProt Q60187
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