MolNFT v1 · #32862 · protein
Three dimensional structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from mycobacterium tuberculosis
2C2Y · Methylenetetrahydrofolate dehydrogenase…: “Three dimensional structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from…”. X-ray diffraction, 1 pocket (best druggability 0.61). MolNFT v1 #32862 on…
- PDB
- 2C2Y
- Type
- protein
- Length
- 280 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methylenetetrahydrofolate dehydrogenase- methenyltetrahydrofolate cyclohydrolase
- EC
- 1.5.1.5, 3.5.4.9
- UniProt
- O50385
- Pockets
- 1 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methylenetetrahydrofolate dehydrogenase- methenyltetrahydrofolate cyclohydrolase (EC 1.5.1.5, 3.5.4.9) | protein | 280 | 43% helix, 18% strand | O50385 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 372 | 0.61 | 0.77 | 43 | empty |
Compared structures
- 2C2Y · Three Dimensional Structure of bifunctional methylenetetrahydrofolate… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O50385
- Elsewhere: RCSB PDB 2C2Y · PDBe 2C2Y · UniProt O50385
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