MolNFT v1 · #32722 · protein
Negative stain EM reconstruction of M.TUBERCULOSIS ACR1(HSP 16.3) fitted with wheat shsp dimer
2BYU · Heat shock protein 16.9B: “Negative stain EM reconstruction of M.TUBERCULOSIS ACR1(HSP 16.3) fitted with wheat shsp dimer”. Electron microscopy, 20 pockets (best druggability 0.62). MolNFT v1 #32722 on GenesisL1: 3D structure…
- PDB
- 2BYU
- Type
- protein
- Length
- 1,212 residues
- Chains
- 12
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock protein 16.9B
- UniProt
- Q41560
- Pockets
- 20 · best druggability 0.62
Structure
electron microscopy · 1 distinct chain · 6% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L | Heat shock protein 16.9B | protein | 101 | 6% helix, 49% strand | Q41560 |
Pockets
20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 170 | 0.62 | 0.84 | 31 | empty |
| 2 | 167 | 0.61 | 0.84 | 31 | empty |
| 3 | 174 | 0.61 | 0.83 | 31 | empty |
| 4 | 169 | 0.61 | 0.83 | 31 | empty |
| 5 | 168 | 0.61 | 0.83 | 26 | empty |
Interfaces
24 interfaces between chains.
- G–H · 1563 Ų buried · 37 hydrogen bonds · protein-protein
- I–J · 1562 Ų buried · 37 hydrogen bonds · protein-protein
- C–D · 1561 Ų buried · 37 hydrogen bonds · protein-protein
- A–B · 1560 Ų buried · 37 hydrogen bonds · protein-protein
- K–L · 1559 Ų buried · 37 hydrogen bonds · protein-protein
Compared structures
- 2BYU · Negative stain EM reconstruction of M.tuberculosis Acr1(Hsp 16.3) fitted with wheat sHSP… · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q41560
- Elsewhere: RCSB PDB 2BYU · PDBe 2BYU · UniProt Q41560
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.