MolNFT v1 · #32679 · protein
Human serum albumin complexed with myristate and iodipamide
2BXN: “Human serum albumin complexed with myristate and iodipamide”. X-ray diffraction, 2 ligands (MYR, IDB), 5 pockets (best druggability 0.90). MolNFT v1 #32679 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2BXN
- Type
- protein
- Length
- 582 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serum albumin
- UniProt
- P02768
- Ligands
- MYR, IDB
- Pockets
- 5 · best druggability 0.90
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serum albumin | protein | 582 | 73% helix, 0% strand | P02768 |
Ligands and binding sites
- MYR · Myristic acid · ligand · 6 copies · chains A
- IDB · 3-[5-[(3-carboxy-2,4,6-triiodo-phenyl)carbamoyl]pentanoylamino]-2,4,6-triiodo-benzoic acid · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1133 | 0.90 | 0.92 | 126 | MYR, IDB |
| 2 | 425 | 0.75 | 0.84 | 36 | MYR |
| 3 | 291 | 0.70 | 0.84 | 39 | MYR |
| 4 | 118 | 0.60 | 0.86 | 18 | MYR |
| 5 | 68 | 0.47 | 0.83 | 16 | IDB |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02768
- Elsewhere: RCSB PDB 2BXN · PDBe 2BXN · UniProt P02768
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.