MolNFT v1 · #32678 · protein
Human serum albumin complexed with myristate and indomethacin
2BXM: “Human serum albumin complexed with myristate and indomethacin”. X-ray diffraction, 2 ligands (MYR, IMN), 6 pockets (best druggability 0.90). MolNFT v1 #32678 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2BXM
- Type
- protein
- Length
- 582 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serum albumin
- UniProt
- P02768
- Ligands
- MYR, IMN
- Pockets
- 6 · best druggability 0.90
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serum albumin | protein | 582 | 73% helix, 0% strand | P02768 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1151 | 0.90 | 0.92 | 127 | MYR, IMN |
| 2 | 273 | 0.73 | 0.86 | 25 | MYR, IMN |
| 3 | 262 | 0.68 | 0.84 | 38 | MYR |
| 4 | 82 | 0.59 | 0.88 | 15 | MYR |
| 5 | 144 | 0.57 | 0.82 | 18 | empty |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02768
- Elsewhere: RCSB PDB 2BXM · PDBe 2BXM · UniProt P02768
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.