MolNFT v1 · #32540 · protein

Structure-function studies of the rmsa csra post-transcriptional global regulator protein family reveals a class of RNA-binding structure

2BTI · Carbon storage regulator homolog: “Structure-function studies of the rmsa csra post-transcriptional global regulator protein family reveals a…”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.34). MolNFT v1 #32540…

PDB: 2BTI
Type: protein
Length: 115 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Carbon storage regulator homolog
Ligands: SO4
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 2 distinct chains · 17% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Carbon storage regulator homolog	protein	58	19% helix, 53% strand	—
B	Carbon storage regulator homolog	protein	57	16% helix, 54% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A, B
ACT · Acetate ion · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.34	0.75	14	empty

Interfaces

1 interface between chains.

A–B · 2072 Å² buried · 38 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

2BTI · Structure-function studies of the RmsA CsrA post-transcriptional global regulator protein… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2BTI · PDBe 2BTI

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