MolNFT v1 · #32400 · protein + DNA
Atomic structure of single-stranded DNA bacteriophage PHIX174 and its functional implications
2BPA · Protein (subunit of bacteriophage PHIX174): “Atomic structure of single-stranded DNA bacteriophage PHIX174 and its functional implications”. X-ray diffraction, 8 pockets (best druggability 0.58). MolNFT v1 #32400 on GenesisL1: 3D…
- PDB
- 2BPA
- Type
- protein + DNA
- Length
- 641 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (subunit of bacteriophage PHIX174); DNA (5'-D(*AP*AP*AP*AP*C)-3')
- UniProt
- P03641, P03643, P69592
- Pockets
- 8 · best druggability 0.58
Structure
x-ray diffraction · 4 distinct chains · 17% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | Protein (subunit of bacteriophage PHIX174) | protein | 426 | 26% helix, 29% strand | P03641 |
| 2 | Protein (subunit of bacteriophage PHIX174) | protein | 175 | 0% helix, 52% strand | P03643 |
| 3 | Protein (subunit of bacteriophage PHIX174) | protein | 36 | 0% helix, 3% strand | P69592 |
| A | DNA (5'-D(*AP*AP*AP*AP*C)-3') | dna | 4 | — | — |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 349 | 0.58 | 0.76 | 34 | empty |
| 2 | 351 | 0.56 | 0.75 | 43 | empty |
| 3 | 301 | 0.53 | 0.75 | 34 | empty |
| 4 | 107 | 0.51 | 0.82 | 17 | empty |
| 5 | 64 | 0.41 | 0.81 | 27 | empty |
Interfaces
4 interfaces between chains.
- 1–3 · 1183 Ų buried · 11 hydrogen bonds · protein-protein
- 1–2 · 203 Ų buried · 1 hydrogen bond · protein-protein
- 1–A · 199 Ų buried · 2 hydrogen bonds · protein-nucleic
- 3–A · 175 Ų buried · 7 hydrogen bonds · protein-nucleic
Compared structures
- 2BPA · Atomic structure of single-stranded DNA bacteriophage PHIX174 and its functional… · the same entry in another collection · chain 1 against 1, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03641
- Every structure of UniProt P03643
- Every structure of UniProt P69592
- Elsewhere: RCSB PDB 2BPA · PDBe 2BPA · UniProt P03641 · UniProt P03643 · UniProt P69592
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