MolNFT v1 · #32217 · protein
X-ray structure of human TPC6
2BJN · Trafficking protein particle complex subunit 6B: “X-ray structure of human TPC6”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.64). MolNFT v1 #32217 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2BJN
- Type
- protein
- Length
- 289 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Trafficking protein particle complex subunit 6B
- UniProt
- Q86SZ2
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 2 distinct chains · 51% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Trafficking protein particle complex subunit 6B | protein | 141 | 50% helix, 18% strand | Q86SZ2 |
| B | Trafficking protein particle complex subunit 6B | protein | 148 | 51% helix, 16% strand | Q86SZ2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.64 | 0.93 | 22 | empty |
| 2 | 180 | 0.62 | 0.84 | 26 | SO4 |
Interfaces
1 interface between chains.
- A–B · 1262 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86SZ2
- Elsewhere: RCSB PDB 2BJN · PDBe 2BJN · UniProt Q86SZ2
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