MolNFT v1 · #3197 · protein

T52V mutant human lysozyme

1CKG · Protein (lysozyme): “T52V mutant human lysozyme”. X-ray diffraction, 2 pockets (best druggability 0.56). MolNFT v1 #3197 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1CKG
Type: protein
Length: 260 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (lysozyme)
EC: 3.2.1.17
UniProt: P61626
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein (lysozyme) (EC 3.2.1.17)	protein	130	38% helix, 12% strand	P61626

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	226	0.56	0.78	26	empty
2	101	0.36	0.74	17	empty

Interfaces

1 interface between chains.

A–B · 393 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

1CKG · T52V mutant human lysozyme · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61626
Elsewhere: RCSB PDB 1CKG · PDBe 1CKG · UniProt P61626

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.