MolNFT v1 · #31869 · protein

Crystal structure of the interleukin-4 variant F82D

2B8X: “Crystal structure of the interleukin-4 variant F82D”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #31869 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2B8X
Type: protein
Length: 129 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Interleukin-4
UniProt: P05112
Ligands: SO4

Structure

x-ray diffraction · 1 distinct chain · 61% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Interleukin-4	protein	129	61% helix, 5% strand	P05112

Ligands and binding sites

SO4 · Sulfate ion · ion · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2B8X · Crystal structure of the interleukin-4 variant F82D · the same entry in another collection · chain A against A, TM-score 1.00
P05112 · AlphaFold monomer V2.0 prediction for interleukin-4 (P05112) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05112
Elsewhere: RCSB PDB 2B8X · PDBe 2B8X · UniProt P05112

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