MolNFT v1 · #31803 · protein
X-ray structure of lens aquaporin-0 (AQP0) (lens mip) in an open pore state
2B6P · Lens fiber major intrinsic protein: “X-ray structure of lens aquaporin-0 (AQP0) (lens mip) in an open pore state”. X-ray diffraction, 2 pockets (best druggability 0.53). MolNFT v1 #31803 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2B6P
- Type
- protein
- Length
- 261 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lens fiber major intrinsic protein
- UniProt
- P06624
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 63% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lens fiber major intrinsic protein | protein | 261 | 63% helix, 0% strand | P06624 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 199 | 0.53 | 0.78 | 29 | empty |
| 2 | 73 | 0.29 | 0.72 | 16 | empty |
Compared structures
- 2B6P · X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state · the same entry in another collection · chain A against A, TM-score 1.00
- P06624 · AlphaFold monomer V2.0 prediction for lens fiber major intrinsic protein (P06624) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06624
- Elsewhere: RCSB PDB 2B6P · PDBe 2B6P · UniProt P06624
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