MolNFT v1 · #31794 · protein

Cryo EM structure of dengue complexed with crd of dc-sign

2B6B · Envelope glycoprotein: “Cryo EM structure of dengue complexed with crd of dc-sign”. Electron microscopy, 1 pocket (best druggability 0.29). MolNFT v1 #31794 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2B6B
Type: protein
Length: 1,295 residues
Chains: 4
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Envelope glycoprotein; CD209 antigen
UniProt: Q96QQ4
Pockets: 1 · best druggability 0.29

Structure

electron microscopy · 2 distinct chains · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Envelope glycoprotein	protein	389	0% helix, 0% strand	—
D	CD209 antigen	protein	128	0% helix, 0% strand	Q96QQ4

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.29	0.72	15	empty

Interfaces

3 interfaces between chains.

A–C · 155 Å² buried · 0 hydrogen bonds · protein-protein
B–C · 42 Å² buried · 0 hydrogen bonds · protein-protein
A–B · 39 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

2B6B · Cryo EM structure of Dengue complexed with CRD of DC-SIGN · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96QQ4
Elsewhere: RCSB PDB 2B6B · PDBe 2B6B · UniProt Q96QQ4

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