MolNFT v1 · #31632 · protein

N-terminal gaf domain of transcriptional pleiotropic repressor cody.

2B18 · GTP-sensing transcriptional pleiotropic repressor cody: “N-terminal gaf domain of transcriptional pleiotropic repressor cody.”. X-ray diffraction, 1 ligand (ILE), 1 pocket (best druggability 0.46). MolNFT v1 #31632 on GenesisL1: 3D…

PDB: 2B18
Type: protein
Length: 155 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GTP-sensing transcriptional pleiotropic repressor cody
UniProt: P39779
Ligands: ILE
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GTP-sensing transcriptional pleiotropic repressor cody	protein	155	41% helix, 23% strand	P39779

Ligands and binding sites

ILE · Isoleucine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.46	0.81	15	ILE

Compared structures

2B18 · N-terminal GAF domain of transcriptional pleiotropic repressor CodY. · the same entry in another collection · chain A against A, TM-score 1.00
P39779 · AlphaFold monomer V2.0 prediction for GTP-sensing transcriptional pleiotropic repressor… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39779
Elsewhere: RCSB PDB 2B18 · PDBe 2B18 · UniProt P39779

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