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MolNFT v1 · #31354 · protein + RNA

Structure of a mycobacterium tuberculosis nusa-RNA complex

2ASB · Ribosomal RNA (5'- gaacucaauag -3'): “Structure of a mycobacterium tuberculosis nusa-RNA complex”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1 #31354 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2ASB
Type
protein + RNA
Length
237 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ribosomal RNA (5'- gaacucaauag -3'); Transcription elongation protein nusa
UniProt
P0A5M2
Pockets
1 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 31% helix, 32% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
BRibosomal RNA (5'- gaacucaauag -3')rna11——
ATranscription elongation protein nusaprotein22631% helix, 32% strandP0A5M2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1570.410.8313empty

Interfaces

1 interface between chains.

  • B–A · 1167 Ų buried · 24 hydrogen bonds · protein-nucleic

Compared structures

  • 2ASB · Structure of a Mycobacterium tuberculosis NusA-RNA complex · the same entry in another collection · chain B against B, TM-score 1.00

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