MolNFT v1 · #3119 · protein
Pnp oxidase from saccharomyces cerevisiae
1CI0 · Protein (pnp oxidase): “Pnp oxidase from saccharomyces cerevisiae”. X-ray diffraction, 1 ligand (FMN), 5 pockets (best druggability 0.74). MolNFT v1 #3119 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1CI0
- Type
- protein
- Length
- 409 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (pnp oxidase)
- EC
- 1.4.3.5
- UniProt
- P38075
- Ligands
- FMN
- Pockets
- 5 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (pnp oxidase) (EC 1.4.3.5) | protein | 205 | 28% helix, 35% strand | P38075 |
| B | Protein (pnp oxidase) (EC 1.4.3.5) | protein | 204 | 28% helix, 35% strand | P38075 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 518 | 0.74 | 0.82 | 43 | FMN |
| 2 | 529 | 0.73 | 0.82 | 50 | FMN |
| 3 | 71 | 0.73 | 0.97 | 22 | empty |
| 4 | 56 | 0.35 | 0.79 | 19 | empty |
| 5 | 51 | 0.29 | 0.76 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 2493 Ų buried · 46 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38075
- Elsewhere: RCSB PDB 1CI0 · PDBe 1CI0 · UniProt P38075
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