MolNFT v1 · #31184 · protein

Crystal structure of L122V/L132V mutant of nitrophorin 2

2AMM: “Crystal structure of L122V/L132V mutant of nitrophorin 2”. X-ray diffraction, 1 ligand (HEM), 1 pocket (best druggability 0.69). MolNFT v1 #31184 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2AMM
Type: protein
Length: 180 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nitrophorin 2
UniProt: Q26241
Ligands: HEM
Pockets: 1 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Nitrophorin 2	protein	180	13% helix, 47% strand	Q26241

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	299	0.69	0.83	34	HEM

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2AMM · Crystal structure of L122V/L132V mutant of nitrophorin 2 · the same entry in another collection · chain X against X, TM-score 1.00
Q26241 · AlphaFold monomer V2.0 prediction for nitrophorin-2 (Q26241) · a predicted model of the same protein · chain X against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q26241
Elsewhere: RCSB PDB 2AMM · PDBe 2AMM · UniProt Q26241

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