MolNFT v1 · #31181 · protein

Solution structure of the calcium-loaded N-terminal sensor domain of centrin

2AMI · Caltractin: “Solution structure of the calcium-loaded N-terminal sensor domain of centrin”. Solution nmr, 1 pocket (best druggability 0.39). MolNFT v1 #31181 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2AMI
Type: protein
Length: 76 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Caltractin
UniProt: P05434
Pockets: 1 · best druggability 0.39

Structure

solution nmr · 1 distinct chain · 61% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Caltractin	protein	76	61% helix, 8% strand	P05434

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.39	0.77	18	empty

Compared structures

2AMI · Solution Structure Of The Calcium-loaded N-Terminal Sensor Domain Of Centrin · the same entry in another collection · chain A against A, TM-score 1.00
P05434 · AlphaFold monomer V2.0 prediction for caltractin (P05434) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05434
Elsewhere: RCSB PDB 2AMI · PDBe 2AMI · UniProt P05434

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