Crystal structure of native protein C activator from the venom of copperhead snake agkistrodon contortrix contortrix

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 35% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A
• SO4 · Sulfate ion · ion · 3 copies · chains A
• ACT · Acetate ion · additive · chains A
• GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 6 disulfide, 3 glycan (disulfide, N-glycosylation).

Compared structures

• 2AIP · Crystal structure of native protein C activator from the venom of copperhead snake… · the same entry in another collection · chain A against A, TM-score 1.00
• P09872 · AlphaFold monomer V2.0 prediction for protein C activator (P09872) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P09872
• Elsewhere: RCSB PDB 2AIP · PDBe 2AIP · UniProt P09872