MolNFT v1 · #30977 · protein
The crystal structure of putative precorrin isomerase cbic in cobalamin biosynthesis
2AFR · Cobalamin biosynthesis precorrin isomerase: “The crystal structure of putative precorrin isomerase cbic in cobalamin biosynthesis”. X-ray diffraction, 1 pocket (best druggability 0.23). MolNFT v1 #30977 on GenesisL1: 3D structure…
- PDB
- 2AFR
- Type
- protein
- Length
- 216 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cobalamin biosynthesis precorrin isomerase
- EC
- 5.4.1.2
- UniProt
- Q8EXP7
- Pockets
- 1 · best druggability 0.23
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cobalamin biosynthesis precorrin isomerase (EC 5.4.1.2) | protein | 216 | 55% helix, 10% strand | Q8EXP7 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.23 | 0.72 | 14 | empty |
Compared structures
- 2AFR · The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis · the same entry in another collection · chain A against A, TM-score 1.00
- Q8EXP7 · AlphaFold monomer V2.0 prediction for cobalt-precorrin-8 methylmutase (Q8EXP7) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8EXP7
- Elsewhere: RCSB PDB 2AFR · PDBe 2AFR · UniProt Q8EXP7
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