MolNFT v1 · #30796 · protein + RNA
Tar RNA recognition by a cyclic peptidomimetic of tat protein
2A9X · Biv tar RNA: “Tar RNA recognition by a cyclic peptidomimetic of tat protein”. Solution nmr, 1 pocket (best druggability 0.36). MolNFT v1 #30796 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2A9X
- Type
- protein + RNA
- Length
- 42 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Biv tar RNA; Biv-2 cyclic peptide
- Pockets
- 1 · best druggability 0.36
Structure
solution nmr · 2 distinct chains · 0% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 2 | Biv tar RNA | rna | 28 | — | — |
| 1 | Biv-2 cyclic peptide | protein | 14 | 0% helix, 14% strand | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 126 | 0.36 | 0.73 | 24 | empty |
Interfaces
1 interface between chains.
- 2–1 · 644 Ų buried · 21 hydrogen bonds · protein-nucleic
Compared structures
- 2A9X · TAR RNA recognition by a cyclic peptidomimetic of Tat protein · the same entry in another collection · chain 2 against 2, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2A9X · PDBe 2A9X
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