MolNFT v1 · #30551 · RNA
Crystal structure of the RNA subunit of ribonuclease P. bacterial a- type.
2A2E · RNA subunit of RNase P: “Crystal structure of the RNA subunit of ribonuclease P. bacterial a- type.”. X-ray diffraction, 1 ligand (OS), 12 pockets (best druggability 0.62). MolNFT v1 #30551 on GenesisL1: 3D structure, binding sites…
- PDB
- 2A2E
- Type
- RNA
- Length
- 266 nucleotides
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA subunit of RNase P
- Ligands
- OS
- Pockets
- 12 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA subunit of RNase P | rna | 266 | — | — |
Ligands and binding sites
- OS · Osmium ion · metal · 17 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 491 | 0.62 | 0.77 | 22 | OS |
| 2 | 628 | 0.61 | 0.74 | 29 | OS |
| 3 | 363 | 0.60 | 0.78 | 24 | OS |
| 4 | 463 | 0.54 | 0.72 | 26 | empty |
| 5 | 208 | 0.48 | 0.76 | 16 | empty |
Compared structures
- 2A2E · Crystal structure of the RNA subunit of Ribonuclease P. Bacterial A-type. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2A2E · PDBe 2A2E
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