MolNFT v1 · #30545 · protein
Atomic-resolution crystal structure of the second SH3 domain of yeast BZZ1 determined from a pseudomerohedrally twinned crystal
2A28 · BZZ1 protein: “Atomic-resolution crystal structure of the second SH3 domain of yeast BZZ1 determined from a…”. X-ray diffraction, 1 pocket (best druggability 0.64). MolNFT v1 #30545 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2A28
- Type
- protein
- Length
- 216 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- BZZ1 protein
- UniProt
- P38822
- Pockets
- 1 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | BZZ1 protein | protein | 54 | 6% helix, 48% strand | P38822 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 507 | 0.64 | 0.76 | 40 | empty |
Interfaces
5 interfaces between chains.
- B–D · 287 Ų buried · 1 hydrogen bond · protein-protein
- A–B · 196 Ų buried · 1 hydrogen bond · protein-protein
- B–C · 187 Ų buried · 2 hydrogen bonds · protein-protein
- A–D · 175 Ų buried · 2 hydrogen bonds · protein-protein
- A–C · 11 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2A28 · Atomic-resolution crystal structure of the second SH3 domain of yeast Bzz1 determined… · the same entry in another collection · chain D against D, TM-score 1.00
- P38822 · AlphaFold monomer V2.0 prediction for protein BZZ1 (P38822) · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P38822
- Elsewhere: RCSB PDB 2A28 · PDBe 2A28 · UniProt P38822
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