MolNFT v1 · #30453 · DNA
Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-a-a-C-G-T-T-G-G, and a molecular explanation of specificity
274D · DNA (5'-D(*CP*CP*AP*AP*CP*GP*TP*TP*(DRUG)GP*G)- 3'): “Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-a-a-C-G-T-T-G-G, and a molecular…”. X-ray diffraction, 1 ligand (ANT). MolNFT v1 #30453 on GenesisL1: 3D…
- PDB
- 274D
- Type
- DNA
- Length
- 10 nucleotides
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*CP*CP*AP*AP*CP*GP*TP*TP*(DRUG)GP*G)- 3')
- Ligands
- ANT
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA (5'-D(*CP*CP*AP*AP*CP*GP*TP*TP*(DRUG)GP*G)- 3') | dna | 10 | — | — |
Ligands and binding sites
- ANT · Anthramycin · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 274D · Crystal structure of a covalent DNA-drug adduct: anthramycin bound to… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 274D · PDBe 274D
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