MolNFT v1 · #30186 · protein
Crystal structure of the yersinia type III secretion protein ysce
1ZW0: “Crystal structure of the yersinia type III secretion protein ysce”. X-ray diffraction, 4 pockets (best druggability 0.48). MolNFT v1 #30186 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1ZW0
- Type
- protein
- Length
- 479 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type III secretion protein
- UniProt
- Q7ARI1
- Pockets
- 4 · best druggability 0.48
Structure
x-ray diffraction · 6 distinct chains · 88% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E | Type III secretion protein | protein | 65 | 86% helix, 0% strand | Q7ARI1 |
| B | Type III secretion protein | protein | 59 | 90% helix, 0% strand | Q7ARI1 |
| C | Type III secretion protein | protein | 52 | 88% helix, 0% strand | Q7ARI1 |
| D, H | Type III secretion protein | protein | 66 | 83% helix, 0% strand | Q7ARI1 |
| F | Type III secretion protein | protein | 52 | 92% helix, 0% strand | Q7ARI1 |
| G | Type III secretion protein | protein | 54 | 89% helix, 0% strand | Q7ARI1 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 176 | 0.48 | 0.77 | 29 | empty |
| 2 | 105 | 0.41 | 0.77 | 20 | empty |
| 3 | 139 | 0.40 | 0.74 | 22 | empty |
| 4 | 80 | 0.31 | 0.73 | 15 | empty |
Interfaces
17 interfaces between chains.
- E–F · 1249 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 1187 Ų buried · 6 hydrogen bonds · protein-protein
- G–H · 1140 Ų buried · 4 hydrogen bonds · protein-protein
- C–D · 1100 Ų buried · 8 hydrogen bonds · protein-protein
- E–H · 443 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 1ZW0 · Crystal structure of the Yersinia Type III Secretion protein YscE · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7ARI1
- Elsewhere: RCSB PDB 1ZW0 · PDBe 1ZW0 · UniProt Q7ARI1
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