MolNFT v1 · #30086 · protein

Crystal structure of human potassium channel kv beta-subunit (KCNAB2)

1ZSX · Voltage-gated potassium channel beta-2 subunit: “Crystal structure of human potassium channel kv beta-subunit (KCNAB2)”. X-ray diffraction, 2 ligands (NAP, CL), 1 pocket (best druggability 0.71). MolNFT v1 #30086 on GenesisL1: 3D…

PDB: 1ZSX
Type: protein
Length: 323 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Voltage-gated potassium channel beta-2 subunit
UniProt: Q13303
Ligands: NAP, CL
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Voltage-gated potassium channel beta-2 subunit	protein	323	53% helix, 16% strand	Q13303

Ligands and binding sites

NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
CL · Chloride ion · ion · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	297	0.71	0.85	50	CL, NAP

Compared structures

1ZSX · Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2) · the same entry in another collection · chain A against A, TM-score 1.00
Q13303 · AlphaFold monomer V2.0 prediction for voltage-gated potassium channel subunit beta-2… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13303
Elsewhere: RCSB PDB 1ZSX · PDBe 1ZSX · UniProt Q13303

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