MolNFT v1 · #300 · DNA
Crystal structure of a double-stranded DNA decamer containing a cisplatin interstrand cross-link adduct
1A2E · DNA (5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3'): “Crystal structure of a double-stranded DNA decamer containing a cisplatin interstrand cross-link adduct”. X-ray diffraction, 1 ligand (CPT). MolNFT v1 #300 on GenesisL1: 3D structure…
- PDB
- 1A2E
- Type
- DNA
- Length
- 20 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3'); DNA (5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3')
- Ligands
- CPT
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA (5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3') | dna | 10 | — | — |
| B | DNA (5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3') | dna | 10 | — | — |
Ligands and binding sites
- CPT · Cisplatin · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 520 Ų buried · 33 hydrogen bonds · nucleic-nucleic
Compared structures
- 1A2E · Crystal structure of a double-stranded DNA decamer containing a cisplatin interstrand… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1A2E · PDBe 1A2E
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