MolNFT v1 · #29938 · protein

NMR structure of antizyme isoform 1 from rat

1ZO0 · Ornithine decarboxylase antizyme: “NMR structure of antizyme isoform 1 from rat”. Solution nmr, 2 pockets (best druggability 0.71). MolNFT v1 #29938 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1ZO0
Type: protein
Length: 126 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ornithine decarboxylase antizyme
UniProt: P54370
Pockets: 2 · best druggability 0.71

Structure

solution nmr · 1 distinct chain · 17% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ornithine decarboxylase antizyme	protein	126	17% helix, 33% strand	P54370

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	143	0.71	0.90	29	empty
2	163	0.67	0.87	32	empty

Compared structures

1ZO0 · NMR structure of antizyme isoform 1 from rat · the same entry in another collection · chain A against A, TM-score 1.00
P54370 · AlphaFold monomer V2.0 prediction for ornithine decarboxylase antizyme 1 (P54370) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54370
Elsewhere: RCSB PDB 1ZO0 · PDBe 1ZO0 · UniProt P54370

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