MolNFT v1 · #29822 · protein
Crystal structure of transcriptional regulator, tetr family (TM1030) from thermotoga maritima at 2.30 a resolution
1ZKG: “Crystal structure of transcriptional regulator, tetr family (TM1030) from thermotoga maritima at 2.30 a…”. X-ray diffraction, 1 ligand (UNL), 3 pockets (best druggability 0.77). MolNFT v1 #29822 on GenesisL1: 3D structure, binding…
- PDB
- 1ZKG
- Type
- protein
- Length
- 399 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, tetr family
- UniProt
- Q9X0C0
- Ligands
- UNL
- Pockets
- 3 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 83% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, tetr family | protein | 200 | 84% helix, 1% strand | Q9X0C0 |
| B | Transcriptional regulator, tetr family | protein | 199 | 83% helix, 1% strand | Q9X0C0 |
Ligands and binding sites
- UNL · Unknown ligand · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 785 | 0.77 | 0.81 | 60 | UNL |
| 2 | 694 | 0.77 | 0.81 | 44 | UNL |
| 3 | 70 | 0.34 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1308 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 14 modified (engineered).
Compared structures
- 1ZKG · Crystal structure of Transcriptional regulator, TETR family (tm1030) from Thermotoga… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0C0
- Elsewhere: RCSB PDB 1ZKG · PDBe 1ZKG · UniProt Q9X0C0
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