MolNFT v1 · #29719 · protein

Crystal structure of selenomethionine substituted isoflavanone 4'-O- methyltransferase

1ZHF · Isoflavanone 4'-O-methyltransferase: “Crystal structure of selenomethionine substituted isoflavanone 4'-O- methyltransferase”. X-ray diffraction, 1 ligand (SAH), 1 pocket (best druggability 0.74). MolNFT v1 #29719 on GenesisL1: 3D…

PDB: 1ZHF
Type: protein
Length: 357 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Isoflavanone 4'-O-methyltransferase
UniProt: Q29U70
Ligands: SAH
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Isoflavanone 4'-O-methyltransferase	protein	357	52% helix, 16% strand	Q29U70

Ligands and binding sites

SAH · S-adenosyl-L-homocysteine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	977	0.74	0.77	64	empty

Compared structures

1ZHF · Crystal structure of selenomethionine substituted isoflava 4'-O-methyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
Q29U70 · AlphaFold monomer V2.0 prediction for isoflavone 4'-O-methyltransferase (Q29U70) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q29U70
Elsewhere: RCSB PDB 1ZHF · PDBe 1ZHF · UniProt Q29U70

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