MolNFT v1 · #29692 · protein

1.35 ångström structure of the kelch domain of KEAP1

1ZGK · Kelch-like ech-associated protein 1: “1.35 ångström structure of the kelch domain of KEAP1”. X-ray diffraction, 1 pocket (best druggability 0.74). MolNFT v1 #29692 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1ZGK
Type: protein
Length: 288 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Kelch-like ech-associated protein 1
UniProt: Q14145
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Kelch-like ech-associated protein 1	protein	288	0% helix, 49% strand	Q14145

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	560	0.74	0.82	52	empty

Modifications

Observed in the structure: 7 modified (engineered).

Compared structures

1ZGK · 1.35 angstrom structure of the Kelch domain of Keap1 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14145
Elsewhere: RCSB PDB 1ZGK · PDBe 1ZGK · UniProt Q14145

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