MolNFT v1 · #29685 · protein
Chalcone reductase complexed with NADP+ at 1.7 ångström resolution
1ZGD: “Chalcone reductase complexed with NADP+ at 1.7 ångström resolution”. X-ray diffraction, 1 ligand (NAP), 7 pockets (best druggability 0.73). MolNFT v1 #29685 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1ZGD
- Type
- protein
- Length
- 616 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chalcone reductase
- UniProt
- Q40309
- Ligands
- NAP
- Pockets
- 7 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Chalcone reductase | protein | 308 | 37% helix, 16% strand | Q40309 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 452 | 0.73 | 0.82 | 49 | NAP |
| 2 | 471 | 0.72 | 0.82 | 51 | NAP |
| 3 | 71 | 0.39 | 0.78 | 19 | empty |
| 4 | 73 | 0.38 | 0.78 | 19 | empty |
| 5 | 83 | 0.38 | 0.77 | 20 | empty |
Compared structures
- 1ZGD · Chalcone Reductase Complexed With NADP+ at 1.7 Angstrom Resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q40309
- Elsewhere: RCSB PDB 1ZGD · PDBe 1ZGD · UniProt Q40309
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.