MolNFT v1 · #29560 · protein
Crystal structure of the NA+/H+ antiporter nhaa
1ZCD · NA(+)/H(+) antiporter 1: “Crystal structure of the NA+/H+ antiporter nhaa”. X-ray diffraction, 13 pockets (best druggability 0.85). MolNFT v1 #29560 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1ZCD
- Type
- protein
- Length
- 752 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NA(+)/H(+) antiporter 1
- UniProt
- P13738
- Pockets
- 13 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 61% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | NA(+)/H(+) antiporter 1 | protein | 376 | 61% helix, 3% strand | P13738 |
Pockets
13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1102 | 0.85 | 0.86 | 110 | empty |
| 2 | 69 | 0.69 | 0.95 | 21 | empty |
| 3 | 281 | 0.69 | 0.84 | 40 | empty |
| 4 | 253 | 0.68 | 0.84 | 34 | empty |
| 5 | 113 | 0.51 | 0.81 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 1418 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13738
- Elsewhere: RCSB PDB 1ZCD · PDBe 1ZCD · UniProt P13738
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