MolNFT v1 · #29554 · protein

Crystal structure of putative N-acetylglucosamine kinase from chromobacterium violaceum. northeast structural genomics target CVR23.

1ZC6 · Probable N-acetylglucosamine kinase: “Crystal structure of putative N-acetylglucosamine kinase from chromobacterium violaceum. northeast structural…”. X-ray diffraction, 2 pockets (best druggability 0.62). MolNFT v1 #29554 on…

PDB: 1ZC6
Type: protein
Length: 578 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable N-acetylglucosamine kinase
UniProt: Q7NU07
Pockets: 2 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable N-acetylglucosamine kinase	protein	285	46% helix, 19% strand	Q7NU07
B	Probable N-acetylglucosamine kinase	protein	293	44% helix, 20% strand	Q7NU07

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	480	0.62	0.76	45	empty
2	415	0.59	0.75	48	empty

Interfaces

1 interface between chains.

A–B · 768 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

1ZC6 · Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum.… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7NU07
Elsewhere: RCSB PDB 1ZC6 · PDBe 1ZC6 · UniProt Q7NU07

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