MolNFT v1 · #29506 · protein
Crystal structure of A.FULGIDUS RIO2 kinase complexed with ATP and manganese ions
1ZAO · RIO2 serine kinase: “Crystal structure of A.FULGIDUS RIO2 kinase complexed with ATP and manganese ions”. X-ray diffraction, 3 ligands (ATP, MN, PO4), 2 pockets (best druggability 0.62). MolNFT v1 #29506 on GenesisL1: 3D structure…
- PDB
- 1ZAO
- Type
- protein
- Length
- 271 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RIO2 serine kinase
- UniProt
- O30245
- Ligands
- ATP, MN, PO4
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RIO2 serine kinase | protein | 271 | 44% helix, 21% strand | O30245 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · chains A
- MN · Manganese (II) ion · metal · 2 copies · chains A
- PO4 · Phosphate ion · ion · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 291 | 0.62 | 0.79 | 29 | MN, PO4, ATP |
| 2 | 69 | 0.34 | 0.76 | 18 | empty |
Compared structures
- 1ZAO · Crystal Structure of A.fulgidus Rio2 Kinase Complexed With ATP and Manganese Ions · the same entry in another collection · chain A against A, TM-score 1.00
- O30245 · AlphaFold monomer V2.0 prediction for rio-type SERINE/THREONINE- protein kinase RIO2… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O30245
- Elsewhere: RCSB PDB 1ZAO · PDBe 1ZAO · UniProt O30245
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.